Sigma Offers Another Format of the RNAi Consortium shRNA Libraries
News Oct 07, 2005
Sigma, a division of Sigma-Aldrich Corporation, through an exclusive agreement with The RNAi Consortium (TRC), has announced the expansion of the MISSION TRC shRNA library product lines to include lentiviral transduction particles in addition to the previously released purified plasmid DNA and frozen bacterial glycerol stock format.
According to Sigma, they are the first to market comprehensive lentiviral shRNA clone libraries in this format, allowing researchers to quickly and efficiently knockdown gene expression in primary, dividing, and non-dividing cells.
This format of the shRNA clones, which target human and mouse genes for RNAi- mediated gene silencing, designed for a faster, broader and reliable shRNA delivery.
Back in 2009, researchers identified a herd of Awassi sheep suffering from "day blindness". As that term implies, these sheep were blind during the day (in bright light) but could see at night, in low-light conditions. After identifying the genetic basis of this blindness, researchers have now successfully used gene therapy to restore their daytime vision.READ MORE