Takeda, Sanford-Burnham Launch Heart Failure Collaboration
News May 29, 2015
Sanford-Burnham Medical Research Institute at Lake Nona said today it is launching a two-year partnership with Takeda Pharmaceutical focused on treating heart failure. The value of the collaboration was not disclosed.
Researchers from Takeda and Sanford-Burnham will join colleagues from the institute’s Conrad Prebys Center for Chemical Genomics to screen its library of compounds.
The researchers aim to identify a molecule that can reactivate metabolism in heart failure patients by restoring the heart’s ability to burn nutritional fuels for pump function.
“My team and colleagues at the Institute have been studying the machinery that controls metabolism in the heart for years. The partnership with Takeda will accelerate our progress and bring it closer to the clinic,” Daniel P. Kelly, M.D., Tavistock distinguished professor and scientific director of Sanford-Burnham at Lake Nona, said in a statement.
The new collaboration is the third between Sanford-Burnham and Takeda over the past five years. The partners launched their first collaboration in 2011, focused on identifying and validating obesity-related biomarkers and new drug targets, as well as speeding up development of new obesity treatments along with Florida Hospital—with which the institute runs a Translational Research Institute for Metabolism and Diabetes. The partnership was renewed in 2013.
Cancer Cells’ Energy Source Blocked by Natural CompoundNews
Researchers have not only untangled an unusual wiring system that cancer cells use for carbohydrate metabolism, but also identified a natural compound that appears to selectively shut down this system in laboratory studies.READ MORE
How do Poison Frogs Protect Themselves Against Their Own Neurotoxin?News
Scientists are a step closer to resolving a related head-scratcher, how do these frogs keep from poisoning themselves?READ MORE
The Ancient Behaviour of Sleep, Conserved Throughout EvolutionNews
The finding that jellyfish sleep implies that sleep is an ancient behavior, largely untouched by millennia of evolution.READ MORE