The Next Phase of Life-Sciences Spaceflight Research: Harnessing the Power of Functional Genomics
News Apr 02, 2012
Spaceflight appears to induce metabolic changes in all species yet studied, many of which are suggested to have detrimental consequences for crew health and performance. These (mal)adaptations represent a major obstacle preventing the worlds’ space agencies from safely achieving their common goal of sending humans on long duration deep-space exploratory missions, and ultimately the human habitation of other planetary bodies. To overcome this obstacle we must first understand the molecular mechanisms regulating spaceflight-induced alterations and, second, utilize this knowledge to effectively target efforts to develop therapeutic strategies.
This article is published online in Communicative and Integrative Biology and is free to access.
Gene-edited Pigs are Resistant to Billion-dollar VirusNews
Scientists have produced pigs that can resist one of the world’s most costly animal diseases, by changing their genetic code. Tests with the virus – called Porcine Reproductive and Respiratory Syndrome, or PRRS – found the pigs do not become infected at all. The animals show no signs that the change in their DNA has had any other impact on their health or wellbeing.READ MORE
Eating Activates Calorie-Burning FatNews
The importance of the human brown adipose tissue (BAT) has become clearer during the past ten years. Coldness is one of the most effective activators of the BAT metabolic function but, in rodents, eating has also been shown to activate BAT. The debate on whether eating has the same effect on humans has lasted for decades. Now, the researchers at Turku PET Centre have proven that having a meal increases oxygen consumption in human BAT to the same extent as coldness.READ MORE