Thomson Reuters Launches new Developments to Support Synthetic Chemists
News Aug 14, 2009
Thomson Reuters announced the newest release of Prous Science Integrity developed in response to demand from synthetic chemists in pharmaceutical and fine chemical companies.
The redesigned Organic Synthesis Knowledge Area within Prous Science Integrity allows researchers to directly retrieve intermediates and reagents, as well as synthesis schemes, to pinpoint key characteristics of synthesis route components in seconds.
New visualizations and filtering methods plus incorporation of the latest industry standard chemical taxonomony (InChIs) enable new research approaches that save time. All these new capabilities can be applied to the foundation of 19,000 schemes of synthesis and 85,000+ structure-searchable intermediates that make Prous Science Integrity a resource to synthetic chemists in the pharmaceuticals and fine chemicals industries.
Pharmaceutical synthetic chemists will value this improved support to identify competitor activity, evaluate newly designed synthetic routes and locate suppliers of selected intermediates, while chemists at fine chemicals companies will be able to identify what new drugs are in development and at what phase, giving them the opportunity to promote their existing chemicals, develop new intermediates or highlight alternative steps in a synthesis scheme.
"Prous Science Integrity is being developed to encompass the new paradigm of translational research," said Josep Prous, Jr., Ph.D., Vice President and Chief Scientific Officer at Thomson Reuters. "The features found in this most recent version support the quality data and innovative functionality that customers have come to expect from Thomson Reuters."
Thomson Reuters will be attending the 238th American Chemical Society's National Meeting and Exposition, August 16-20, 2009 in Washington, DC and ChemOutsourcing, September 14-16, 2009 in Long Branch, NJ. Researchers are encouraged to come and receive a demonstration of the latest changes to Prous Science Integrity.
In a new study in cells, University of Illinois researchers have adapted CRISPR gene-editing technology to cause the cell’s internal machinery to skip over a small portion of a gene when transcribing it into a template for protein building. This gives researchers a way not only to eliminate a mutated gene sequence, but to influence how the gene is expressed and regulated.
Researchers published today a detailed description of the complete genome of bread wheat, the world's most widely-cultivated crop. This work will pave the way for the production of wheat varieties better adapted to climate challenges, with higher yields, enhanced nutritional quality and improved sustainability.