We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience, read our Cookie Policy

Why CRISPR Doesn't Always Work

News   Jul 11, 2018 | Original Press Release from the University of Illinois at Chicago

 
Why CRISPR Doesn't Always Work

UIC researchers show persistent Cas9 binding to a double strand break causes CRISPR genome editing to fail about 15 percent of the time. When RNA polymerases collide with Cas9 from one direction (template orientation), they can dislodge Cas9 and increase genome editing efficiency. Credit: Ryan Clarke, et al)

 
 
 

RELATED ARTICLES

Does Our Environment Affect the Genes in Our Brains?

News

Is there a link between differences in IQ test performance and the activity of certain genes? Researchers have shown that modifications in the structure of a specific gene have a negative impact on individual test performance. This suggests that environmentally-induced epigenetic changes to our genetic material have a greater impact on intelligence than previously thought.

READ MORE

Genome Duplication Drives Evolution of Species

News

Polyploid plants have a duplicate set of chromosomes. As a result, large-scale genetic changes are therefore possible in the new species, making it more adaptable in comparison with the parental species, as has now been proven by UZH researchers with rockcress.

READ MORE

Peeking Inside Pickles

News

Food scientists have mapped and characterized microbial populations in a vegetable fermentation facility, helping to resolve the question of how microbes are transferred within the facility.

READ MORE

 

Like what you just read? You can find similar content on the communities below.

Analysis & Separations

To personalize the content you see on Technology Networks homepage, Log In or Subscribe for Free

LOGIN SUBSCRIBE FOR FREE