XDx Selects Ingenuity Systems for Pathways Solution
News Jul 12, 2007
Ingenuity Systems has announced that XDx has licensed Ingenuity’s flagship solution IPA 5.0. Ingenuity Systems was selected by XDx after a comprehensive evaluation of several pathway analysis products.
XDx is a molecular diagnostics company based in Brisbane, California. The company has developed a new method for noninvasively monitoring the immune system by measuring gene expression in a patient’s peripheral blood. The technology can offer the potential to improve the quality of life for patients with a variety of life-threatening or life-altering immune-mediated diseases.
"We chose IPA because it best meets our objective to identify and understand biomarkers associated with immune-mediated diseases,” commented Dr. Tod Klingler, VP of Informatics at XDx.
“IPA provides us with access to its extensive knowledge base of gene function information assembled from the scientific literature through easy-to-use tools that our researchers can use to rapidly evaluate candidate biomarkers. Specifically, IPA allows us to make sense of our gene expression data in the context of known immune system interactions and pathways.”
Genome-wide association studies (GWAS) look at large populations to find genes that contribute to common, multi-gene traits like height or obesity. These comprehensive studies frequently turn up large numbers of tiny genetic variations that occur more often in people who are tall, obese, etc. So which genes should scientists investigate further?READ MORE
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