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Applications of chemically modified synthetic guide RNA for CRISPR-Cas9 genome editing
Applications of chemically modified synthetic guide RNA for CRISPR-Cas9 genome editing

Megan Basila, Eldon Chou, Emily Anderson, Melissa L. Kelley, Anja van Brabant Smith

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Ion Torrent next generation sequencing for accurate genotyping and detection of resistance associated variants in HCV and HIV
Detecting resistance associated variants in HCV and HIV

Elian Rakhmanaliev, Pramila Ariyaratne, Charlie Lee, Pornpimon Nimitsuntiwong, Chortip Wathtphan, Ekawat Passomsub, Kok Siong Poon, Cui Wen Chua, Mui Joo Khoo, Zhang Rui, Wen Huang, Evelyn S. Koay, Wasun Chantratita, Gerd Michel

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Highly Accurate HCV Genotyping by Targeted Next Generation Sequencing
Highly Accurate HCV Genotyping by Targeted Next Generation Sequencing

Kok Siong Poon, Evelyn S. Koay, Cui Wen Chua, Mui Joo Khoo, Zhang Rui, Elian Rakhmanaliev, Wen Huang, Gerd Michel

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Strategies for Improving RNAi Screening Success: Using a Ubiquitin-EGFP Assay to Identify Druggable Genes Required for Proteasome Function
Strategies for Improving RNAi Screening Success: Using a Ubiquitin-EGFP Assay to Identify Druggable Genes Required for Proteasome Function

Anja van Brabant Smith, Elena Maksimova, Matthew Brenton, Mark Deiparine, Rachel Edwards, Phoenix Kwan, Amanda Birmingham, Devin Leake

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A Novel Cell-Free DNA Extraction System for Cancer Diagnostics
A Novel Cell-Free DNA Extraction System for Cancer Diagnostics

Amanda Fan, Alex Yeo, Yin Kum Ng, Elian Rakhmanaliev, Pramila Ariyaratne, Charlie Lee, Gerd Michel, Tatiana Ivanova

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CRISPR-Cas9 genome editing utilizing chemically synthesized RNA
CRISPR-Cas9 genome editing utilizing chemically synthesized RNA

Michael Delaney, Kaizhang He, Eldon Chou, Amanda Haas, ┼Żaklina Strezoska, Melissa L. Kelley, and Anja van Brabant Smith Dharmacon, part of GE Healthcare, 2650 Crescent Drive, Lafayette, CO 80026, USA

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The Chemical Synthesis of Long and Highly Modified RNA using 2'-ACE Chemistry
The Chemical Synthesis of Long and Highly Modified RNA using 2'-ACE Chemistry

Xiaoqin Cheng, Kristina Larson, Letitia Kwok, David Mierzejewski, Shawn Begay, Randy Rauen, Kelly Grimsley, Kaizhang He, Michael Delaney, David Kitchen, Amanda Haas, Melissa Kelley, Anja van Brabant Smith

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Experimental design considerations for efficient and specific gene  knockin using a CRISPR-Cas9 for HDR with synthetic crRNA and tracrRNA
Experimental design considerations for efficient and specific gene knockin using a CRISPR-Cas9 for HDR with synthetic crRNA and tracrRNA

Hidevaldo B. Machado, John A. Schiel, Maren Mayer-Gross, Eldon T. Chou, Melissa L. Kelley, Anja van Brabant Smith. Dharmacon, part of GE Healthcare, 2650 Crescent Drive, Lafayette, CO 80026, USA

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Resistance-Associated Variants in HCV Genotype 1 Populations
Resistance-Associated Variants in HCV Genotype 1 Populations

Elian Rakhmanaliev1, Pramila Ariyaratne1, Zhang Rui1, Kok Siong Poon2, Cui Wen Chua2, Mui Joo Khoo2, Evelyn S. Koay2, Ekawat Passomsub3, Wasun Chantratita3, Gerd Michel1

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