Latest Posters
Poster
Highly Accurate HCV Genotyping by Targeted Next Generation Sequencing
The recent fast advancement of next generation sequencing (NGS) technologies allowing for unprecedented speed and accuracy in analyzing viral genomes are opening new ways to further improve diagnostic genotyping of HCV.
Poster
Detecting resistance associated variants in HCV and HIV
Objectives: to develop improved detection of clinically relevant viral mutations using ion torrent based NGS in an automated workflow.
Poster
Strategies for Improving RNAi Screening Success: Using a Ubiquitin-EGFP Assay to Identify Druggable Genes Required for Proteasome Function
This poster describes the approaches used to ensure effective delivery of siRNA molecules and to identify robust siRNA controls. It also provides the strategies used to validate compatibility of the RNAi automation platform with the phenotype being analyzed.
Poster
Optimized Workflow for Single Cell Copy Number Profiling Using High Resolution Oligo CGH Arrays
Here we describe GenetiSure Pre-Screen, a same day, cost-effective, analysis workflow that combines whole genome amplification (WGA) with copy number (CN) profiling using high-resolution oligo CGH microarrays.
Poster
Functional Analysis of RAD51B and RAD23B SNPs using Circular Chromosome Conformation Capture (4C) in Human Prostate Cell Lines
The aim of this study is to understand the mechanism behind the association between single nucleotide polymorphisms (SNPs), lying in non-coding regions near or within RAD51B and RAD23B, and prostate cancer risk by analysing their interactions with the whole genome using Circular Chromosome Conformation Capture (4C).
Poster
A Novel Cell-Free DNA Extraction System for Cancer Diagnostics
We developed a magnetic bead-based cfDNA extraction kit and integrated it into the automated qPCR- and NGS-based IVD workflows. In this study we are compering this magnetic beads-based cfDNA extraction system with a column-based method.
Poster
CRISPR-Cas9 genome editing utilizing chemically synthesized RNA
Chemical synthesis has been easily applied for rapidly generating either crRNA and tracrRNA or synthetic sgRNA for direct delivery into cells for gene editing applications such as DNA-free options and high throughput arrayed screening.
Poster
The Chemical Synthesis of Long and Highly Modified RNA using 2'-ACE Chemistry
Dharmacon has previously developed a novel RNA synthesis chemistry making RNA synthesis as reliable, accessible and of comparable quality as routinely observed in DNA synthesis.
Poster
Experimental design considerations for efficient and specific gene knockin using a CRISPR-Cas9 for HDR with synthetic crRNA and tracrRNA
Precise genome engineering with CRISPR-Cas9 and single-stranded DNA oligo or double-stranded DNA plasmid donors via homology-directed repair (HDR).
Poster
Resistance-Associated Variants in HCV Genotype 1 Populations
In this study we specifically investigated RAVs emerging in HCV genotype 1.
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