Latest Posters
Poster
Integrated Next-Generation Sequencing and qPCR Workflow in Clinical Diagnostics
Combined automated qPCR and NGS Sentosa workflow is a reliable and efficient in vitro diagnostics (IVD) tool for the detection and/or quantitation of a wide range of bacterial and viral pathogens as well as gene mutations.
Poster
A Synthetic CRISPR-Cas9 System for Homology-directed Repair
Synthetic, dual-RNA-encoded Cas9 is used for precise homology-directed repair (HDR) gene engineering. Both short and long (GFP) inserts are covered.
Poster
CRISPR-Cas9 Genome Editing Utilizing Chemically Synthesized RNA
CRISPR-Cas9 gene editing using synthetic crRNA:tracrRNA or sgRNA is highly efficient and easy to use. Synthetic crRNA:tracrRNA is uniquely suited to in vitro and in vivo applications, in particular, DNA-free approach with Cas9 mRNA. Chemical synthesis of guide RNAs allows accurate and rapid production of arrayed crRNA libraries for high-confidence, loss-of-function screens.
Poster
Customizable Exon-centric Target Enrichment Strategy for Copy Number and SNP Analysis
Agilent’s Custom OneSeq provides a comprehensive, flexible, and cost-effective means to identify exon-level copy number changes as well as SNP/INDEL in one assay.
Poster
Advanced Microfluidic Mixing Device for the Study of Macromolecule Dynamics
We have developed and characterized a micro-fluidic mixer to study the macro-molecule dynamics such as kinetics of protein folding, DNA sequencing, single molecule study and detection etc. on a micro-second timescale. Numerical simulation has been performed to analyse the study of mixing performance of micro-fluidics channel.
Poster
DNA-free CRISPR-Cas9 Genome Engineering in Zebrafish
Poster describing the advantages of a DNA-free gene editing system and the application of this system in zebrafish.
Poster
600 Base Reads on the Ion S5™ Next-Generation Sequencing System Enables Accurate HLA Typing of 96 Samples on One 530™ Chip
We have demonstrated that by combining improvements in templating and sequencing biochemistry we are able to sequence templates longer than 600 bases with high accuracy on an Ion S5 530 chip.
These improvements open the S5 use space to include haplotyping applications that require longer reads. As a demonstration of that, we accurately typed 96 HLA samples on one 530 chip.
These improvements open the S5 use space to include haplotyping applications that require longer reads. As a demonstration of that, we accurately typed 96 HLA samples on one 530 chip.
Poster
Assessing Diversity in Cassava through the Application of Metabolomics
In the present study metabolomic platforms have been established for Cassava and used to assess the biodiversity present in Cassava germplasm collections and elucidate underlying biochemical mechanisms associated with traits of interest.
Poster
Addressing False Positive Variants Arising from Pseudogenes
Clinical genetic testing has been transformed in recent years by the introduction of Next-Generation Sequencing (NGS).
Poster
The Challenges of Genetic Testing in Patients Diagnosed with Breast Cancer; The Kent Oncology Centre Experience
In this study we explore retrospective data to determine strategies for optimizing the genetic referral pathways for breast cancer.
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