A New Approach to Increase Yields and Improve Functionality of Recombinant Proteins
Poster Dec 05, 2013
Antti Vasala, BioSilta Oy, Oulu, Finland
Most frequently, bacteria are grown in shake flasks or plates using commercially-available or ‘in-house’ adaptations of LB, TB or M9. Ehen supplied with a carbon source such as glucose, bacteria grow and divide rapidly at their maximum growth rate. However, as uncontrolled growth and fast aerobic metabolism deplete oxygen and glucose levels and alter the surrounding pH, bacteria soon switch over to anaerobic metabolism.
Histone Deacetylase 6 (HDAC6) As A Therapeutic Target in Chronic Lymphocytic LeukemiaPoster
This study investigates the role of histone deacetylase 6 (HDAC6) in chronic lymphocytic leukemia and establishes it as a novel therapeutic target for the treatment of this disease.READ MORE
Inhibition of The Auto-inflammation Suppressor Protein ISG15 Triggers Preeclampsia by Blocking Trophoblast Migration and InvasionPoster
In summary, ISG15 expression levels are crucial for trophoblast morphology and function (migration/invasion). By blocking trophoblast invasion, reduced ISG15 levels could contribute to impaired spiral artery transformation that reduces utero-placental blood flow in preeclampsia. Thus, agents inducing ISG15 expression are likely to be therapeutic in preeclampsia.
Comparison of CD45+ Depletion Methods for Enrichment of Disseminated Tumor Cells in Bone Marrow SamplesPoster
Comparison of CD45+ depletion methods for enrichment of disseminated tumor cells in bone marrow samples.READ MORE