Dymension 2D Gel Dymension 2D Gel Analysis Software
Ibogaine, an indole alkaloid present in the root of plant
Tabernanthe iboga has been shown to have anti-addiction
properties against opiates1, 2, stimulants3 and alcohol4. Since the
anti-addiction effect lasts longer than the presence of ibogaine in
the body, metabolic changes are occurring in the brain which
could be studied using a 2D gel based proteomics approach. The
protein profiles could then be used to establish which proteins are
up or down-regulated and may lead to a better understanding of
the pharmacodynamics of anti-addiction therapies. However, to be
able to detect which proteins in a complex 2D gel image are being
expressed requires sophisticated software to resolve protein spot
images quickly and easily.
Tabernanthe iboga has been shown to have anti-addiction
properties against opiates1, 2, stimulants3 and alcohol4. Since the
anti-addiction effect lasts longer than the presence of ibogaine in
the body, metabolic changes are occurring in the brain which
could be studied using a 2D gel based proteomics approach. The
protein profiles could then be used to establish which proteins are
up or down-regulated and may lead to a better understanding of
the pharmacodynamics of anti-addiction therapies. However, to be
able to detect which proteins in a complex 2D gel image are being
expressed requires sophisticated software to resolve protein spot
images quickly and easily.
