Low-cost wind tunnel for micro-arthropods
Poster Aug 24, 2009
Here we describe a construction of wind tunnel suitable for close-up observation of micro-arthropods behavior under various conditions. The tunnel was made of glass with inner dimensions 6x6x110 centimeters. Both the inlet and outlet compartments were equipped with an electric fan, series of plastic diffusers and a metal mesh to minimize wind turbulence inside a 40 centimeters-long observation chamber in the middle of the tunnel.
Genome-wide association studies (GWAS) have identified more than 100 genetic loci associated with type 2 diabetes. The majority of these are located in the intergenic or intragenic regions suggesting that the implicated variants may alter chromatin conformation. This, in turn, is likely to influence the expression of nearby or more remotely located genes to alter beta cell function. At present, however, detailed molecular and functional analyses are still lacking for most of these variants. We recently analysed one of these loci and mapped five causal variants in an islet-specific enhancer cluster within the STARD10 gene locus. Here, we aimed to understand how these causal variants influence b-cell function by alteration of the chromatin structure of enhancer clusterREAD MORE
Early life stress (ELS) is highly associated with development of psychopathology
and mood disorders in adulthood. Genetic studies have identified variation in the gene calcium voltage-gated channel subunit alpha1C (CACNA1C) to increase risk for several psychiatric disorders. This poster assessed the expression of Cacna1c following prepubertal stress.