Preclinical Data with siRNA Targeting WNT Pathway for Breast Cancer Treatment
Abstract
The aim of present study was focused on the effect of silencing target gene in triggering of apoptosis in breast cancer MCF-7 cells. Flow cytometry, light-, confocal microscopy and viability/cytotoxicity tests were used for evaluation of the protein level, percentage of apoptotic cells and morphological features of cell death.
The aim of present study was focused on the effect of silencing target gene in triggering of apoptosis in breast cancer MCF-7 cells. Flow cytometry, light-, confocal microscopy and viability/cytotoxicity tests were used for evaluation of the protein level, percentage of apoptotic cells and morphological features of cell death.
