SAMPL - Sampling And Model-Selection PipeLine : Systematically Combining Stable Gene Selection and Classification
Poster Apr 05, 2007
Two goals of gene expression analysis are classification and gene selection. Combinations of gene selectors with classifiers were evaluated on random subsets of arrays. Consensus gene signatures are constructed from genes frequently selected. Model reliability is estimated by the variance of the classification performances. The method finds reliable models, even when classification performance is variable. Manual literature screening verified the relevance of the genes identified from an osteoarthritis dataset.
Despite the developments in conventional PCR, the complexity of multiplex Real Time PCR is still limited due to the lack of sufficient detection channels. To achieve high-end multiplexing capacity on standard Real Time PCR machines, Anapa Biotech has developed the MeltPlex® technology (see box on right).READ MORE