Stealth-Adapted Viruses and Viteria: Insights into Virus Construction, Replication and Potential Therapies
Poster Dec 11, 2013
W. John Martin
Stealth-adaptation is a mechanism that allows cytopathic viruses to evade immune elimination through the deletion of genes coding the major antigens targeted by the cellular immune system. A prototype stealth-adapted virus, repeatedly cultured from a patient with chronic fatigue syndrome (CFS) was cloned and partially sequenced. It has a fragmented, genetically unstable, genome.
Performance of the D5000 and High Sensitivity D5000 ScreenTape Assays for the 4200 TapeStation SystemPoster
Here, we focus on quantification, sizing, and sensitivity of both D5000 ScreenTape assays.READ MORE
MHV68 Infection in a Novel rag2 F62L/F62L Mouse Model Based on a Patient with CID-G/AI PhenotypePoster
MHV-68 infection in our rag2 mouse model induced increased antibody responses to virus and self and inflammatory disease in end organs. Major mechanism of inflammatory infiltrates and autoantibody generation is yet to be determinedREAD MORE