Synthetic Life - Ethics for a New Biology
Poster Oct 09, 2007
Synthetic biology allows for the direct chemical synthesis of any gene, operon and chromosome. Not only does synthetic biology facilitate copying and editing existing genetic information, it also instantly permits the creation of any imaginable completely novel genetic information without being constrained by nature.
We currently do not have any references for these new realities because they were not previously thinkable by whatever scientific, philosophicalor religious ideas we could consider. With the advent of synthetic biology and bioethics we are, in the end, creating a new common thinking space, which is not only about behavior norms or research protocols, but also about creating a new reality, both in the physical world and in the mind.
Despite the developments in conventional PCR, the complexity of multiplex Real Time PCR is still limited due to the lack of sufficient detection channels. To achieve high-end multiplexing capacity on standard Real Time PCR machines, Anapa Biotech has developed the MeltPlex® technology (see box on right).READ MORE
Genome-wide association studies (GWAS) have identified more than 100 genetic loci associated with type 2 diabetes. The majority of these are located in the intergenic or intragenic regions suggesting that the implicated variants may alter chromatin conformation. This, in turn, is likely to influence the expression of nearby or more remotely located genes to alter beta cell function. At present, however, detailed molecular and functional analyses are still lacking for most of these variants. We recently analysed one of these loci and mapped five causal variants in an islet-specific enhancer cluster within the STARD10 gene locus. Here, we aimed to understand how these causal variants influence b-cell function by alteration of the chromatin structure of enhancer clusterREAD MORE
Early life stress (ELS) is highly associated with development of psychopathology
and mood disorders in adulthood. Genetic studies have identified variation in the gene calcium voltage-gated channel subunit alpha1C (CACNA1C) to increase risk for several psychiatric disorders. This poster assessed the expression of Cacna1c following prepubertal stress.