Affymetrix Adds Mouse and Rat Arrays to Gene 1.0 ST System
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Affymetrix Inc. has announced the full commercial launch of the GeneChip® Mouse and Rat Gene 1.0 ST Arrays, the latest additions to the Gene 1.0 ST Array System. The arrays provide researchers with an accurate and informative alternative for mouse and rat gene expression detection, all in an easy-to-use format.
Similar to the recently launched Human Gene 1.0 ST Array, the Mouse and Rat Gene 1.0 ST Arrays use the Whole Transcript (WT) Sense Target Labeling Assay to deliver a more complete and accurate view of a gene’s total transcriptional activity, not just the 3’ end of a gene like traditional expression array designs.
The Gene 1.0 ST Arrays complement the comprehensive GeneChip® Exon 1.0 ST Arrays, which offer both gene-level expression profiling and alternative splicing analysis in a single experiment.
“The new Mouse and Rat Gene 1.0 ST Arrays feature a particularly efficient design with better coverage of the core transcriptome,” said Robert W. Williams, Ph.D., lead developer of the GeneNetwork web site at the University of Tennessee. “I expect that these technical improvements when combined with lower cost will encourage researchers to implement more powerful and sophisticated experiments using a platform with strong bioinformatics support.”
According to Affymetrix, the Gene 1.0 ST Arrays incorporate the latest available mouse and rat genome sequence information and feature a simplified design strategy, which provides one value from one probe set for each gene. Both the Mouse and Rat 1.0 ST Arrays contain more than 720,000 probes that interrogate more than 27,000 well-annotated genes.
