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BioDiscovery Releases Nexus Copy Number Version 5.1 for DNA Copy Number Analysis and Visualization

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BioDiscovery, Inc. has announced the release of version 5.1 of its Nexus Copy Number software, the user friendly application for DNA copy number analysis. Version 5.1 offers numerous improvements in the user interface allowing for detailed information about a sample and calls to be available at the user's finger tips to review samples, identify possible pathogenic regions, compare with already processed samples, obtain annotations from many external databases, and easily generate customized reports.

A number of improvements to processing include the new FASST2 segmentation algorithm, incorporation of PennCNV processing, and support for Affymetrix OncoScan™ (MIP technology) arrays. With new preprocessing steps, the software can adjust for samples with aneuploidy and correct for any systematic biases (such as GC wave patterns), even samples with a lot of artifacts can be salvaged to extract high quality data for crisp and reliable results.

“Nexus Copy Number has been widely adopted across the globe by researchers at notable academic institutions as well as commercial entities and customers from a wide array of disciplines. These users find Nexus to be a robust, time saving application with flexibility to cater to each individual’s specific needs. Flexibility is a cornerstone of Nexus Copy Number software as our mission is to empower the end user to conduct his own analysis efficiently and accurately” said Soheil Shams, President of BioDiscovery.

“Increasing numbers of users are utilizing Nexus Copy Number not just as an analysis tool for individuals but as a platform for large scale studies involving sharing of data across the globe harnessing the power of Nexus DB, the web-based repository linked with Nexus Copy Number.”
Nexus Copy Number can integrate and process together, in a single project, data from commercial array platforms such as Agilent, Affymetrix, Illumina, Roche NimbleGen, Next Gen read depth, as well as custom arrays. With its free access to a web-based repository for querying, and storing genomic data from any location across the globe, Nexus Copy Number is a powerful solution for large groups such as special consortia.

The software is applicable to many types of studies from focused projects of a cytogeneticist to large scale cancer or GWAS studies. BioDiscovery is attuned to such different needs and offers the product in a flexible and modular system to allow users to create configurations that are suited to their needs.