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Bio-Rad Announces the Launch of its CFX384 Real-Time PCR Detection System

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Bio-Rad Laboratories, Inc. has announced the launch of its Bio-Rad CFX384™ real-time PCR detection system as well as its new CFX Manager™ software, Security Edition. CFX Manager can be used to ensure compliance with the regulations published by the U.S. Food and Drug Administration for secure handling of electronic records.

With the CFX384 system, researchers have access to high-throughput real-time PCR in a 384-well format. The CFX384 system can be operated in several control configurations. Researchers can either run a stand-alone system without a computer or up to four instruments from one computer.

Using the Bio-Rad C1000™ thermal cycler chassis as the base thermal cycler instrument, the CFX384 real-time PCR detection system incorporates optical technologies and software to deliver sensitive detection for real-time PCR applications, including absolute quantitation, genetic variation analysis, and gene expression. Multiple data acquisition modes let runs be tailored to suit any application and the compact design fits any laboratory setting.

The CFX384 real-time PCR detection system provides multiple scan modes for data acquisition, so runs can be tailored to different detection chemistries. SYBR® Green I and single-color FAM protocols are completed in less time using the SYBR/FAM only scan mode, which collects data from channel one for all 384 wells in just 8 seconds.

In multichannel scan mode, the system detects fluorescence from channels one through four for all 384 wells in less than 20 seconds, enabling four-target discrimination in a single well. The CFX384 real-time PCR detections system’s optics shuttle includes a channel for single color FRET experiments, further expanding experimental options.