Blaze Away with Selerity Technologies' New Column
Product News Apr 08, 2005
Selerity introduces a new silica-based stationary phase that can withstand temperatures up to 200ºC. The Blaze200™ column opens up a range of new opportunities for the separations scientist looking to take advantage of better results and peak shapes.
According to Selerity although there are a variety of stationary phases such as polymeric and graphitic carbon materials that can be used at elevated temperatures, most HPLC chemists prefer the selectivity and higher efficiencies of silica-based columns.
Increasing temperature can drastically limit the column lifetime when the bonded phase is based on traditional chemistries. Most silica-based HPLC columns can only be used to temperatures up to 60°C and a pH range of 3-8. Such columns have a propensity to degrade as water attacks the underlying support particles.
Selerity's Blaze200 column consists of a polydentate silica phase that is stable at extreme temperatures, with added pH stability. The development of a new polycarbosilane bonding chemistry that is hydrolytically stable against breakdown in aqueous environments facilitates such analyses.
It integrates multiple point attachments to the silica with a high degree of cross-linking. This combination creates a highly protective barrier over the silica backbone, protecting it from hydrolytic attack.
The column offers traditional C18 selectivity, while providing enhanced temperature stability for use up to 200°C and pH conditions as high as 12. Columns based on this chemistry are useful for both isothermal and programmed separations over wide ranges of temperature.