We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience. You can read our Cookie Policy here.

Advertisement
deCODE Launches deCODE T2™ - A DNA-based Test for Assessing Inherited Risk of Type 2 Diabetes
Product News

deCODE Launches deCODE T2™ - A DNA-based Test for Assessing Inherited Risk of Type 2 Diabetes

deCODE Launches deCODE T2™ - A DNA-based Test for Assessing Inherited Risk of Type 2 Diabetes
Product News

deCODE Launches deCODE T2™ - A DNA-based Test for Assessing Inherited Risk of Type 2 Diabetes


Want a FREE PDF version of This Product News?

Complete the form below and we will email you a PDF version of "deCODE Launches deCODE T2™ - A DNA-based Test for Assessing Inherited Risk of Type 2 Diabetes"

First Name*
Last Name*
Email Address*
Country*
Company Type*
Job Function*
Would you like to receive further email communication from Technology Networks?

Technology Networks Ltd. needs the contact information you provide to us to contact you about our products and services. You may unsubscribe from these communications at any time. For information on how to unsubscribe, as well as our privacy practices and commitment to protecting your privacy, check out our Privacy Policy

deCODE Genetics has announced the launch of deCODE T2™, a DNA-based reference laboratory test for the first common and well-validated genetic risk factor for type 2 diabetes (T2D).

deCODE believes this test may provide an important means to better gauge individual risk of T2D and in that help to guide prevention and treatment strategies.

The sequence variant detected by deCODE T2™ is a single SNP (a one letter variation in the sequence of the genome) in the TCF7L2 gene on chromosome 10.

In deCODE’s original findings published last year, and in published replications by independent researchers in studies of tens of thousands of people from populations around the globe, between 8-11% of the general population have been shown to carry two copies of the risk variant, but roughly twice that number of type 2 diabetics.

In other words, having two copies of the risk variant - a positive result for the deCODE T2™ test – has been shown to correspond to an approximate doubling of the likelihood of T2D.

Published studies have also demonstrated that testing for the variant detected by deCODE T2™ can be used to identify pre-diabetics at higher than average risk of progressing to full-blown diabetes, and that these same individuals can effectively counteract this added risk through weight loss and through the use of certain medications.

“Understanding one’s risk of T2D is the first step toward enabling more effective prevention. The principal risk factors for T2D are well known – obesity, unhealthy diet and lack of exercise – and by addressing these individuals can reduce their risk of becoming diabetic. Family history, part of which involves genetic risk factors, also plays a part. deCODE T2™ offers a new tool to help individuals and their doctors bring an understanding of inherited risk into the picture. deCODE T2™ is but the first of several DNA-based predisposition tests we have in development for common diseases,” said Kari Stefansson, CEO of deCODE.

“We believe that as individuals, doctors and healthcare providers begin to integrate these tests as a part of everyday healthcare – much as cholesterol screening has become a part of understanding and reducing risk of heart disease – these tests may provide major benefit to public health,” Stefansson added.

Advertisement