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Eksigent Offers MALDI Spotting Capability with Single-Point Control from NanoLC™

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Eksigent has announced the addition of a NanoLC MALDI Spotting System to its nanoflow chromatography product line.

Featuring the Ekspot spotter, the system complements the company’s existing offerings for nanospray mass spectrometry (MS) proteomics analysis. Integration of the Ekspot with the NanoLC provides single-point control from the Eksigent software. The tool enables the analysis of complex protein and peptide samples with MALDI MS.

“This new capability enables customers to use our powerful NanoLC systems in MALDI applications,” explained Remco van Soest, product manager for Eksigent.

“Our NanoLC is already the leading platform for proteomics applications, and many customers have been using our LC with a third-party spotter. Now we can provide them with a solution that is fully integrated and optimized for our NanoLC,” Soest said.

The Ekspot spotter/fraction collector deposits fractions eluted from the NanoLC onto a MALDI plate, while a built-in pump automatically adds the matrix. High positioning accuracy ensures consistent spotting with maximum resolution. The high-capacity system stores up to sixteen MALDI-targets for high-throughput applications.

The Company claims that by eliminating flow splitting, its microfluidic technology improves reproducibility and sensitivity and eliminates solvent waste. The NanoLC’s microscale flow control runs HPLC gradients at rates as low as 20 nL per minute.