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EPICENTRE’s CircLigase™ Circularize Single-Stranded DNA

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CircLigase™ II ssDNA Ligase from EPICENTRE catalyzes the circularization of single-stranded DNA greater than 15 bases without the need for oligo bridges. Virtually no linear or circular concatamers are produced by the enzyme.

CircLigase II Ligase is an improved version of the original CircLigase enzyme, and is ideal for preparing circular templates from oligos or single-stranded cDNA for rolling-circle replication or rolling-circle transcription assays.