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Exiqon Introduces New Products for Functional Analysis of microRNA Families

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Exiqon A/S has announced the launch of its miRCURY LNA™ microRNA Family Inhibitors for efficient inactivation of microRNA families.

The new miRCURY LNA™ microRNA Family Inhibitors enable researchers to inactivate the biological function of entire microRNA families in just one experiment.

The new LNA™ enabled products offered exclusively by Exiqon will allow scientists to save time and cost and at the same time conduct more robust experiments than previously possible.

Exiqon’s microRNA Family Inhibitors inactivate all microRNAs within a given microRNA family using only a single or a few LNA™ enhanced oligonucleotides.

The required amount of oligonucleotide can be kept at a non-toxic level, as each inhibitor targets more than one microRNA.

In addition, LNA™ increases the binding affinity and the biological stability of the oligonucleotides.

The new miRCURY LNA™ microRNA Family Inhibitors are short antisense oligonucleotide targeting primarily the microRNA seed sequences conserved among members of a specific microRNA family. It is well acknowledged that the seed sequence has an essential role in the initial binding to the mRNAs.

In a comment, Senior Vice President Sales & Marketing, Henrik M. Pfundheller said: “The miRCURY LNA™ microRNA Family Inhibitors meet a strong demand from our customers and has already been tested at a number of beta-test sites resulting in an overwhelming positive feedback. The new product enables faster progress of functional analysis of microRNAs”.

Henrik Pfundheller continues: “The new product offering builds on 6 years of customer experience with our miRCURY LNA™ microRNA Inhibitors, which makes me optimistic about the market potential for our new miRCURY LNA™ microRNA Family Inhibitors”.

All microRNAs are categorized in families according to sequence homology and biological function. The miRCURY LNA™ microRNA Family Inhibitors are available for all the major human microRNA families.