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Fluidigm Introduces First Integrated Fluidic Circuit Able to Perform 9,216 Simultaneous Real-Time PCR Experiments

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Fluidigm Corporation has introduced its BioMark™ 96.96 Dynamic Array, a new integrated fluidic circuit (IFC) capable of performing 9,216 simultaneous real-time PCR experiments running TaqMan® assays in nanoliter quantities.

According to Fluidigm, this new generation IFC can enable life science researchers to achieve logistical efficiency and flexibility, as well as comprehensive profiling from miniscule amounts of sample.

The 96.96 Dynamic Array, the heart of Fluidigm’s BioMark™ Genetic Analysis System, can provide the flexibility of a microwell plate and the density of a microarray in one consumable. IFCs meter, multiplex and combine nanoliter volumes of fluids, with precise control and reproducibility, many thousands of times; in parallel; on a single chip.

Using Fluidigm’s 96.96 Dynamic Array, researchers can set up 9,216 experiments with just 192 pipetting steps.

“Our new BioMark 96.96 Dynamic Array is our most complex and most capable IFC ever -- yet it is simple to use,” said Gajus Worthington, Fluidigm’s President and CEO. “The 96.96 doesn’t require pre-spotting, so researchers have full flexibility to select from the lab’s existing assays to quickly and readily modify experiments.”

The demands of genotyping researchers require high throughput and high call-rates at very low cost. “The 96.96 Dynamic Array delivers greater than 99 percent call rates and can process more than 70,000 genotypes in a day -- all for just over a nickel per data point (using TaqMan assays),” Worthington continued.