Fluidigm Launches BioMark™ System for High-Throughput Real-Time PCR
Product News Apr 27, 2007
Fluidigm Corporation has introduced the BioMark system based on nanofluidic chips for real-time PCR.
Accordingly, the Company has invited scientists engaged in quantitative gene analysis to a web-based event on Thursday, May 10, at 3:00 PM, London time.
The event includes a short presentation by Fluidigm director of R&D, Dr. Marc Unger, and panelist Dr. Rick Gerren of Source MDx, who is a BioMark system user.
According to Company, the chips are known as dynamic arrays, and have important advantages compared to 96-well plates, including: twenty-four times the number of PCR assays per run, significant reductions in reagent costs, less liquid-handling complexity to implement large-scale studies.
The BioMark system is of particular value to scientists who need to simplify the quantitative analysis of 50 to 100 genes against a large number of samples.
BioMark dynamic arrays are tailored for multiplexed gene expression analyses. The array generates 2,304 PCR reactions, requiring orders of magnitude less reagent and liquid transfer steps than traditional formats.
The system also runs BioMark digital arrays, which enable digital PCR - a term established in the scientific literature -which is essential for detection of nucleic acid mutations in a high background of similar sequences. Whereas the practice of digital PCR in microplates has been impractical, it is simple and reliable in Fluidigm digital arrays, the company says.