We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience. You can read our Cookie Policy here.

Advertisement

Homogeneous Assay Kits Minimize Assay Complexity


Want a FREE PDF version of This Product News?

Complete the form below and we will email you a PDF version of "Homogeneous Assay Kits Minimize Assay Complexity"

Technology Networks Ltd. needs the contact information you provide to us to contact you about our products and services. You may unsubscribe from these communications at any time. For information on how to unsubscribe, as well as our privacy practices and commitment to protecting your privacy, check out our Privacy Policy

AMSBIO has released 4 new homogeneous 384-well format AlphaScreen assay kits - JMJD2A, JMJD2B, JMJD2C, PRMT5 and G9a (a histone methyltransferase).

AlphaScreen kits are bead-based ALPHA technology assays, using microparticles coated with either DNA or protein in a format suitable for use with automated reagent handling systems. Each AlphaScreen or AlphaLISA assay contains two bead types, Donor beads and Acceptor beads.

Binding of molecules captured on the beads leads to an energy transfer from one bead to the other, ultimately producing a luminescent / fluorescent signal. This signal can be detected in a plate reader capable of reading 96-, 384- or 1596-well plates. There are two types of beads, one used for AlphaScreening and one for AlphaLISA. The AlphaLISA bead emission (615 nm) is narrower and brighter than the AlphaScreen bead emission (520-620 nm). Conveniently, kits are suitable with either assay format.

These are the first in a series of kits that enables AMSBIO to broaden their offering in Kinase PDE and HDAC Screening and Profiling products and services.
Advertisement