New GeneDirectory Software Provides Band Comparisons in Large Scale Genomics Projects
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Syngene has announced GeneDirectory V2.01, its upgraded automated gel data storage and analysis software is now available. The package has features to enhance ease of use in genetic fingerprinting studies, cluster analysis, VNTR analysis, as well as genotyping and RFLPs.
GeneDirectory now comes with bootstrapping, a random statistical re-sampling technique. Using bootstrapping, GeneDirectory automatically selects bands and re-samples them many times so matching patterns can be assessed for the validity of their matching. The resultant bootstrapping values are displayed alongside the dendrograms. Bootstrapping makes results more accurate by discerning between genuine matches and those where a match is coincidental.
The software, which has a simple to use Windows like folder structure also allows users to view long tracks and permits unlimited elements in a composite track to be used for band matching. The tracks can be analyzed by cluster analysis, profile matching and band matching via a pattern of bands or an entire profile.
The resulting data, aligned dendrograms and aligned track images can also be automatically exported to Excel, making it easier for researchers to determine, as well as store the information they need.
