New Method of Optimizing CHO Cells for Large Scale Bioprocess
Product News Feb 01, 2008
Invitrogen announces PD-Direct™, its fully integrated service for customized bioprocess development, is hosting a Technology Tutorial on developing novel types of CHO cells at 12.35pm on Tuesday, March 4th in the Main Hall of the European Cell Line Development and Engineering Conference being held at the Corinthia Panorama in Prague.
The presentation, entitled "Engineering of Novel Platform Cell Lines with Phenotypic Traits Advantageous for Bioproduction", will help scientists understand how Invitrogen is using its PD-Direct™ Revolution™ technology.
Dr Jonathan Dempsey, Process Science Fellow at Invitrogen PD-Direct™, a scientist with many years’ experience in developing cell culture manufacturing processes and cell lines, will discuss how Revolution™ enables optimization of CHO cells by accelerating gene evolution. This combined with screening and selection techniques can produce cells resistant to high osmolality and therefore better adapted to large scale bioprocess.
Dr Jonathan Dempsey, Process Science Fellow at Invitrogen PD-Directa said: "In recent years, cutting development time to produce profitable biopharmaceuticals is becoming critical for many pharma and biotechs companies. I’m looking forward to presenting the data and to discussing the benefits of using Revolution™ for generating cell lines with improved phenotypic traits for bioprocessing at our Technology Tutorial at European Cell Line Development and Engineering in Prague, because optimizing the host cell line promises to be a powerful new approach to improving large scale bioprocessing.”