Rosetta Biosoftware's Rosetta Syllego System Achieves GeneChip-compatible™ Status with the Affymetrix GeneChip® Microarray Platform
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Rosetta Biosoftware has announced that the Rosetta Syllego™ system has achieved GeneChip-compatible™ status for use with the Affymetrix microarray platform. This compatibility enables research organizations conducting genome-wide association and other genetic studies to focus on revealing genetic risk factors and therapies for diseases, such as coronary artery disease, type 2 diabetes, and other complex diseases.
Genetic studies of complex diseases and traits pose a number of informatics challenges that impede the accurate and reproducible identification of genetic markers of disease and drug response. Through the Affymetrix GeneChip Compatible Program, Affymetrix collaborates with software developers like Rosetta Biosoftware by providing software development tools and guidelines to conquer many of these challenges.
The Rosetta Syllego system overcomes the informatics challenges of genetic studies by providing biologists, statistical geneticists, and investigators responsible for generating genotyping data with tools for data management, quality control, data analysis, and meta-analysis.
The Syllego system brings together genotyping data generated by Affymetrix and other microarray platforms, tools for linking to analysis methods of choice, and project workspaces to organize, analyze, and share data and analysis results.
The Syllego system is also a single repository for easy access to public and private genotyping data sets, reference annotation, and non-clinical and clinical information.
"Genetic studies often generate vast quantities of data, in which lie the keys to understanding the hereditary basis of disease," says Steve Lincoln, Vice President of Informatics of Affymetrix. "The data management and analysis capabilities of the Syllego system allow researchers to focus on their science and make discoveries using these new paradigms in genetic research."
The Syllego system supports the latest Affymetrix Genome-wide Human SNP Array 6.0 and includes data analysis tools along with the ability to integrate study data with common statistical packages, such as R.
The commercial version 1.0 of the Syllego system will be showcased at a workshop at the upcoming 57th annual meeting of the American Society for Human Genetics conference in San Diego, Calif., on October 24.
