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Top Medical School uses Syngene InGenius System

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Researchers in the School of Medicine at the University of Glasgow are using a  Syngene InGenius gel doc system to visualise microbial DNA stained with SYBR®  Green on Temporal Temperature Gradient Electrophoresis polyacrylamide gels.  The information obtained is being used to determine which microflora are  associated with Crohn's Disease and Coeliac Disease in children and could help to determine the most effective methods to treat and control these conditions.

Dr Konstantinos Gerasimidis, Lecturer in Clinical Nutrition at the School of  Medicine, University of Glasgow commented: “We are looking for microbes in children suffering with digestive diseases and are trying to determine those most  prevalent in their colonic samples. For that we use a variety of molecular micro- biology techniques such as Temporal Temperature Gradient Electrophoresis Gels  stained with SYBR Green Nucleic Acids Staining. We prefer to use SYBR Green  for visualising the DNA, rather than Ethidium bromide because it is significantly  more sensitive and less toxic.”


Dr Gerasimidis continued: “We decided to upgrade our gel doc to an InGenius  system because we have found it is more sensitive than other imagers we looked  at in the same price range. We can easily visualise our DNA so we’re pleased we chose an InGenius.”

Laura Sullivan, Syngene’s Divisional Manager, concluded: “Establishing the  potential causes of chronic digestive diseases is critical research and we are excited to hear that the InGenius is playing a part in this. The results researchers at University of Glasgow are obtaining, demonstrate to molecular biologists looking for an inexpensive system to safely and accurately image their DNA, that all they need is an InGenius.”