CosMx™ SMI - Spatial Multiomics Single-cell Platform

Elevate your single cell research with spatial information. The CosMx™ Spatial Molecular Imager (SMI) is here to revolutionize your single-cell and spatial biology research! CosMx SMI is spatial multiomics single-cell imaging solution. It enables rapid quantification and visualization of up to 1,000 RNA and 100 validated protein analytes at single-cell and subcellular resolution in intact Formalin-Fixed Paraffin-Embedded (FFPE) and fresh frozen tissue samples. With a tunable workflow from high-plex to high-throughput, CosMx enables not only discovery research by providing the highest plex and unbiased whole-slide analysis but also translational research with low-plex, high-throughput biology driven analysis. CosMx SMI is an integrated sample-to-result in situ analysis platform. The CosMx SMI platform utilizes easy-to-use sample preparation based on standard ISH/IHC protocols and offers both custom and pre-validated assay panels for reliable results. The combination of sensitive cyclic in situ hybridization chemistry, an ultra-high-resolution imaging readout instrument, and an interactive cloud-based data analysis and visualization software makes the data simple to collect and interpret. CosMx enables researchers to define cell types, cell states, cell atlas and tissue microenvironment phenotypes. CosMx complements single-cell RNA-seq data and provides location information of all cell types. It helps to better understand biological process controlled by ligand-receptor interactions, identify single-cell biomarkers and characterize gene expression networks with spatial context. Be the first to access this fully supported, end-to-end solution from NanoString, an experienced spatial biology leader.