Onyx™ Genome Engineering Platform: The First Benchtop Biofoundry

Now, any lab can be a biofoundry with access to an automated genome editing workflow and ready-to-use reagents, consumables, and intuitive design and analysis software that puts more discovery or functional genomics projects within reach. Scientists can build complex cell libraries in E. coli and S. cerevisiae with a diversity of edit types across the genome, instead of small pools or single individual edits, all from their lab.

• It’s accessible: The sophisticated Onyx instrument was designed to fit on the benchtop and operate with push-button ease and smart automation that controls all aspects of genome engineering experiments
• It’s flexible and versatile: The Onyx platform has a wide range of options to generate diversity, which include introducing both large numbers of edits as well as a broad variety of edit types, such as insertions, deletions and substitutions
• It’s scalable: The Onyx platform opens the floodgates of what is possible. Onyx provides a streamlined design and data analysis pipeline, eliminating the need to build an extensive bioinformatics infrastructure, while robust algorithms enable the design of edits in a single gene to the whole genome
• It’s trackable: Onyx’s iterative design is powered by trackability, which ensures editing designs are properly integrated and documented through each cycle to enable rapid iterations