The truCOLLECT® Solution

The truCOLLECT® Solution is an integrated system designed to simplify and standardize whole blood collection and processing for genomic research. By combining remote, fingerstick-based sample collection with automated, AFA®-powered DNA extraction, the solution enables high-quality analyte recovery with precision, consistency, and scalability across a wide range of downstream applications.

At its core, the truCOLLECT Solution transforms traditional blood collection workflows by removing logistical and technical barriers associated with venipuncture and cold-chain handling. Using a simple fingerstick device, participants can self-collect a small, volumetric sample of whole blood, eliminating the need for clinical visits while maintaining analyte integrity comparable to conventional methods.

Once collected, samples are stabilized at the point of collection, enabling ambient storage and shipping without the need for refrigeration or dry ice. This significantly reduces complexity, cost, and variability in sample handling, particularly for decentralized or geographically distributed studies.

The truCOLLECT workflow is designed for seamless integration into laboratory environments. Standardized extraction and purification processes, powered by Adaptive Focused Acoustics® (AFA®) technology, deliver consistent, high-quality DNA suitable for a broad range of molecular applications, including next-generation sequencing, Sanger sequencing, pharmacogenomics, arrays, and MLPA. The workflow is automation-ready, supporting high-throughput processing and reproducible results across laboratories and study sites. 

A key advantage of the truCOLLECT Solution is its ability to preserve whole blood integrity while enabling reliable and consistent analyte recovery. The system’s volumetric sampling approach ensures uniform input, while ambient stability minimizes pre-analytical variability that commonly affects alternative collection methods. Performance data demonstrate consistent DNA yield and quality across samples and conditions, including extended storage at room temperature and exposure to variable environmental conditions.

The solution includes three core components that work together as a unified workflow: a participant-ready whole blood collection kit for simple self-collection, an extraction kit designed for high-quality DNA recovery from stabilized samples, and AFA-enabled instrumentation for efficient and reproducible processing. Together, these components create a streamlined, single-vendor workflow that reduces manual handling and supports laboratory automation.

By addressing the limitations of traditional blood collection approaches, the truCOLLECT Solution enables broader participant recruitment, simplifies logistics, and improves overall data quality. It is particularly well suited for academic and translational research labs, core facilities, contract research organizations, diagnostic laboratories, and multi-site research programs that require consistent sample input and scalable workflows.

Ultimately, the truCOLLECT Solution shifts blood collection from a bottleneck to a scalable, reliable component of genomic workflows, empowering researchers to generate high-quality data with greater efficiency and confidence.