Twist's cfDNA Library Preparation Kit: Maximize Rare Variant Detection with Confidence

The Twist cfDNA Library Preparation Kit addresses challenges associated with library preparation from circulating cell-free DNA (cfDNA). Liquid biopsies have gained prominence in oncology research, particularly for investigating potential biomarkers within genetic material from tumors circulating in peripheral blood. This kit enables high conversion cfDNA library generation for next-generation sequencing (NGS) on Illumina systems, overcoming the technical challenges associated with low-input and degradation of cfDNA, as well as other samples that are hard to acquire and have limited DNA abundance (i.e. urine and CSF samples).

The Twist cfDNA Library Preparation Kits provide our highest quality library preparation solution, offering not only robust performance with low sample input, but also high conversion rates. The Twist cfDNA Library Preparation Kit and Twist cfDNA Library Preparation and Hyb Mix Kit enable WGS as well as targeted enrichment workflows.