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Cell Culture – News and Features

A 3D graphical representation of a number of Rotavirus virions.
News

Role of Rotavirus Protein in Gastrointestinal Disease Severity Revealed

Researchers revealed that the rotavirus NSP4 protein drives disease severity by disrupting calcium signaling in infected and nearby cells. These disruptions worsen symptoms and trigger immune responses.
A stretch of DNA, with one section illuminated.
News

Two Genes Driving Early Prostate Tumor Formation Discovered

Two newly identified disease-causing genes, known as Bzw2 and Eif5a2, have been implicated in early prostate cancer development.
A target surrounding a cancer cell.
News

Epigenetic Approach Shows Promise for Targeting Colorectal Cancer

Researchers at Johns Hopkins and the Chinese Academy of Sciences discovered that a mouse protein, STELLA, blocks the cancer-associated protein UHRF1, reversing epigenetic changes that promote tumor growth.
White immune cells attack a yellow cancer cell, symbolizing immunotherapy.
News

Off-the-Shelf Immunotherapy Approach Shows Promise for B-Cell Lymphoma

A new type of off-the-shelf cell-based immunotherapy shows promise for B-cell lymphomas, and could make make future cellular immunotherapies less expensive and more accessible.
A young woman led on a sofa suffering from stomach pain. Highlighting the need for gut organoids to study IBD.
Article

Library of Organoid “Mini-Guts” Helps Identify New Pathways in IBD

Technology Networks spoke with Dr. Thomas Dennison, University of Cambridge, to learn more about the advantages of using patient-derived organoids for modeling inflammatory bowel disease (IBD).
Multi-channel pipette, pipetting into wells
News

Genetic Tweak Boosts Drug-Making Cells by Blocking Toxic Byproducts

Researchers have developed a new strategy to enhance pharmaceutical production in Chinese hamster ovary (CHO) cells, which are commonly used to manufacture protein-based drugs for treating cancer, autoimmune diseases and much more.
Cancer cell being attack by white blood cells
News

Cancer Immunotherapy: How Therapeutic Antibodies Do Their Job

A new look at cancer cells: Würzburg researchers show how therapeutic antibodies work – thanks to an innovative method of super-resolution microscopy.
Three in-focus cells with orange nuclei, with many more out of focus behind them.
News

AI Tool Can Predict the Activity of Genes Within Any Human Cell

A new AI tool can accurately predict gene activity within any human cell, revealing the cell's inner mechanisms.
A plastic model of a human heart on a metal stand.
News

Cell-Based Therapy Aids Recovery in a Pig Model of Heart Attacks

The injection of heart muscle spheroids derived from hiPSCs can aid heart attack recovery in animal models.
Double helix structure of DNA.
News

CRISPR Therapy Shows Promise for Muscular Dystrophy in Mice

ECRC researchers developed a CRISPR-based gene therapy targeting dysferlin mutations in muscular dystrophy. By editing and transplanting corrected muscle stem cells, they restored protein function and regrew muscle in preclinical models.
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