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Cell Culture – News and Features

Human immune cells (nucleus: blue, cell boundary: red) with Mycobacterium tuberculosis (green) in the collagen hydrogels.
News

New 3D Model Speeds Up TB Drug Testing

Researchers from the Department of Bioengineering (BE), Indian Institute of Science (IISc), have designed a novel 3D hydrogel culture system that mimics the mammalian lung environment.
A glowing gold trophy.
Industry Insight

SLAS Europe 2024 New Product Award Winners

Two winners earned the New Product Award at SLAS Europe 2024: SEED Biosciences’ Dispen3D and Cryologyx’s PlateReady™. Technology Networks spoke with CEO of CryoLogyx Tom Congdon to learn more about their award-winning new product.
A 3D model of a human kidney.
News

Lab-Made Kidneys Grown With Blood Vessels for the First Time

For the first time scientists managed to generate kidney organoids with a complex vascular system. These are asembloids, micrometric organoids formed by the union of kidney organoids with vascular organoids in 3D.
Double helix structure of DNA.
News

Ancestral Differences Affect Performance of CRISPR-Cas9 Guides in Human Cells

New research shows that many of these CRISPR screening experiments rely on components, called CRISPR/Cas9 guides, that do not perform equally well in cells from people of all ancestries, which can cause CRISPR screens to miss cancer dependencies.
A puzzle that spells the word autism.
News

Brain Cell Overgrowth Before Birth Associated With Autism Severity

Brain organoids derived from toddlers with autism spectrum disorder suggest that subtypes of the condition may have in utero origins. That's according to a new study from researchers at the University of California San Diego, led by Dr. Alysson R. Muotri.
Cancer cells.
News

Gene Identified That Helps Cancer Cells Spread Around the Body

Investigators have identified a gene whose expression confers a growth advantage to metastatic cancer cells, which cause 90% of cancer-related deaths. Silencing this gene in lab models of cancer prevented metastatic cells from growing and spreading.
Cells.
News

Human Derived RNA Integration Fuels Chronic Hepatitis E Virus Infection

Why does Hepatitis E become chronic in some patients, and why do medications not work? To find out, an international research team led by scientists from Bochum observed a patient with chronic Hepatitis E infection over a year.
Page of a calendar showing a month with three consecutive Saturdays circled.
Article

The Friedman Test

The Friedman test can be used to compare repeated measures or samples, such as following a person's biological functions over time. In this article, we consider its assumptions, when to use it and go through a worked example.

ARRALYZE glass array with three different shaped wells highlighted. Each well is enlarged to display a different type of cell.
Industry Insight

Navigating the Complexities of Single-Cell Research

The advent of single-cell analysis has marked a transformative era in the life sciences, particularly in the field of drug development. To delve deeper into the subject, Technology Networks spoke with Dr. Nora Fekete-Drimusz, head of biology at ARRALYZE. We discuss the transformative impact of single-cell analysis on life science research and explore how ARRALYZE's multifunctional single-cell platform can support those working in this area.
Bacteria in an intestine.
News

Novel Antibiotic Kills Pathogenic Bacteria but Spares Healthy Gut Microbes

Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis while sparing healthy microbes in the mouse gut.
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