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Cell Culture – News and Features

A young girl receiving chemotherapy.

Non-Coding DNA Could Explain Childhood Cancer’s Radiotherapy Resistance

Scientists at St. Jude Children’s Research Hospital have discovered non-coding genetic variants contributing to chemotherapy resistance in acute lymphoblastic leukemia.
Diabetes equipment.

Experimental Drug “Hides” Pancreas Cells in Type 1 Diabetes Mouse Models

Scientists at Johns Hopkins Medicine say that an experimental monoclonal antibody drug called mAb43 appears to prevent and reverse the onset of clinical type 1 diabetes in mice, and in some cases, to lengthen the animals’ lifespan.
Microscopy images of mouse thymic epithelial cell (TEC) organoids.

New Organoid Model Offers Insights Into Immune System Training

Researchers from the Organoid group have developed a new organoid model that can be used to study the thymus. The organoids, derived from mouse thymus tissue, specifically model thymic epithelial cells (TECs).
Schematic representation of SemaCyte microcarriers including optical barcodes.
Industry Insight

Tackling Unmet Drug Screening Needs

In this interview, Jeroen Verheyen tells us about Semarion, its SemaCyte technology and how it can help to address unmet drug screening needs.

Lab-Grown Mini-Colons Accurately Mimic Colorectal Tumor Development

In a breakthrough for cancer research, scientists at EPFL have created lab-grown mini-colons that can accurately mimic the development of colorectal tumors, offering a powerful new tool for studying and testing treatments for the disease.
Microscopic image of a group of bacteria cells

Phage Therapies for Multidrug-Resistant Infections Should Consider Host Response

Research has found that therapeutic phages can be detected by epithelial cells of the human respiratory tract and elicit an immune response. These findings suggest that human–host interactions should be a key factor when designing phage therapies.
An image showing the words "prime editing".

Probing the Inner World of Cells Provides Unexpected Boost to Prime Editing

While probing the inner workings of cells, Dr. Britt Adamson, assistant professor of molecular biology at Princeton University, and colleagues discovered a way to boost the efficiency of prime editing.
Rice husk, waste from rice processing.

Rice Bran Nanoparticles Show Promise as Anti-Cancer Agent

Plant-derived nanoparticles, including those from rice bran, could be used as alternatives to traditional cancer treatments.
Fluorescence microscopy images of vpCell Pools.

Novel Method Allows Simultaneous Fluorescent Labeling of Many Proteins

Observing proteins precisely within cells is extremely important for many branches of research but has been a significant technical challenge. A research group has now overcome this hurdle: With a novel method.
A coffee bean between tweezers.

Is Lab-Grown Coffee the Sustainable Brew of the Future?

Dr. Heiko Rischer, head of plant biotechnology at the VTT Technical Research Centre of Finland, breaks down the promise of bioreactor-brewed coffee.