We've updated our Privacy Policy to make it clearer how we use your personal data. We use cookies to provide you with a better experience. You can read our Cookie Policy here.

Advertisement

Drug Kinetics – Multimedia

True High-Throughput Analysis of Transporter Activity Screens content piece image
App Note / Case Study

True High-Throughput Analysis of Transporter Activity Screens

Two key ADME (absorption, distribution, metabolism and excretion) properties used to predict the in -vivo performance of a drug candidate are its ability to permeate a cell membrane and its potential to act as a substrate for transmembrane transporter proteins.
ADME 101 Guide: Which Hepatocyte Test System Should I Use? content piece image
Video

ADME 101 Guide: Which Hepatocyte Test System Should I Use?

This ADME 101 video provides an overview of different types of hepatocytes, their unique benefits, and when you use them for in vitro preclinical DMPK studies.
Assessing Kinetics in Drug Discovery content piece image
Listicle

Assessing Kinetics in Drug Discovery

Download this listicle to learn more about the importance of drug kinetics, key experimental techniques and computational modeling tools.
Navigating the Use of Extracellular Vesicles as Therapeutics content piece image
Listicle

Navigating the Use of Extracellular Vesicles as Therapeutics

Download this listicle to learn more about extracellular vesicles as engineerable drug delivery vehicles, vaccines and from mesenchymal stem cells.
Addressing Unique Challenges With Custom In Vitro Test Systems content piece image
Video

Addressing Unique Challenges With Custom In Vitro Test Systems

In this webinar, Products Director and custom test system expert, Zell Woodworth, will discuss some of the unique challenges his team have solved and the ways custom solutions are designed and executed to help researchers and drug developers meet goals outside the reach of standard in vitro products.
A Vision Engaging Pharmacokinetic Strategies To Treat Substance Abuse Disorders and Overdose content piece image
Video

A Vision Engaging Pharmacokinetic Strategies To Treat Substance Abuse Disorders and Overdose

This video lecture will detail the chemistry, immunology and behavioral findings from vaccines against opioids, including heroin and the synthetic opioids fentanyl and carfentanil, as well as a bacterial source to treat nicotine substance disorders and poisoning.
Eliminating Problems in Drug Development: Understanding the Role of Drug Metabolism content piece image
Video

Eliminating Problems in Drug Development: Understanding the Role of Drug Metabolism

This talk will discuss processes for the metabolism of a drug, referred to as ADME (Absorption, Distribution, Metabolism, Excretion), and the safety testing to provide requisite information to move a drug through IND and into clinical trials. Prior to marketing a new drug and actually prior to administering a candidate drug to humans in clinical trials, it is important to ensure that drug will not only be effective in the therapeutic manner prescribed, but also be safe and not bring any undo harm to patients.
Interaction Qualified Primary Hepatocytes | Lonza Product Overview content piece image
Video

Interaction Qualified Primary Hepatocytes | Lonza Product Overview

Advance your in vitro drug interaction studies to the next level! Watch this video to learn how our Interaction Qualified primary hepatocytes can increase your confidence in your DDI and metabolism studies.
HPLC-Charged Aerosol Detection content piece image
How To Guide

HPLC-Charged Aerosol Detection

The intended function of an excipient is to guarantee the required physicochemical and biopharmaceutical properties of the pharmaceutical preparation.
The Important Role of UDP Glucuronosyltransferases in Drug Metabolism and Drug–Drug Interactions content piece image
Video

The Important Role of UDP Glucuronosyltransferases in Drug Metabolism and Drug–Drug Interactions

The importance of glucuronidation for metabolism of xenobiotics in humans is illustrated by the abundance and broad tissue distribution of the enzymes, the diversity of substrates and reactions catalyzed, as well as a number of distinctive UGT enzymes and their genetic polymorphisms.
Advertisement