Drug Kinetics – News and Features

At the BioTrinity 2025 conference, Technology Networks spoke with Dr. Pedro Correa de Sampaio, co-founder and CEO of Neobe, who are utilizing synthetic biology to engineer bacteria capable of breaking down the barriers within tumors.

Researchers at Tokyo University of Science have developed Chol-HDOs, which efficiently penetrate the brain, overcoming challenges associated with delivering gene-targeting drugs to brain tissue.

Pfizer has announced the decision to discontinue the development of danuglipron, an oral glucagon-like peptide-1 (GLP-1) receptor agonist, which was being investigated for chronic weight management.

A clinical study has found that percutaneous hepatic perfusion using a melphalan hepatic delivery system may help patients with a rare eye cancer that has spread to their liver.

Researchers have developed the first wearable device for measuring gases emitted from and absorbed by the skin, allowing for a new way to measure skin health, wound healing, hydration levels and more.

Researchers have developed a new nanoparticle therapy that tackles obesity through two complementary mechanisms: converting energy-storing white fat into calorie-burning beige fat while simultaneously reducing obesity-related inflammation.

In lab-grown nerve cells from ALS patients, a natural compound found in certain fruits and vegetables helped the cells produce more energy and eased stress in the protein-processing center of the cell called the endoplasmic reticulum.

University of Florida scientists have helped identify a novel drug compound that selectively activates pain-altering receptors in the body, offering a potentially safer alternative to conventional pain medications such as opioids.

Oregon State University researchers have discovered a way to get anti-inflammatory medicine across the blood-brain barrier, opening the door to potential new therapies for a range of neurodegenerative diseases.

Three-dimensional models allow researchers to better represent complex tissues and cell-cell interactions. This article explores the cell models currently used by researchers to understand disease and aid drug discovery.