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Drug Targets – News and Features

A purple human brain.
News

New Biomarkers Could Help Diagnosis of Schizophrenia in Rare Genetic Disorder

A recent study led by UC Davis Health researchers provides new insights into the molecular changes linked to the rare genetic condition 22q11.2 deletion syndrome, or 22q.
A blood pressure monitor around someone's arm.
News

100 New Genomic Regions Linked to Blood Pressure

One of the largest genomics studies into blood pressure has revealed 100 new regions of the genome that influence blood pressure.
A plastic model of a kidney held in a person's hand.
News

50 Genomic Regions Associated With Kidney Cancer Risk Identified

A new analysis has identified 50 new areas across the genome that are linked to kidney cancer susceptibility.
Illustration of a human form
Article

Dissecting the Proteome To Understand Disease

Proteomics provides insights into the regulation of biological processes and mechanisms of disease. In this article, we explore approaches scientists are using to find early markers of disease, new drug targets and strategies to overcome resistance to treatments.
Protein structures.
News

Scientists Uncover the Cellular Functions of Proteins Integral to Inflammatory Diseases

Mount Sinai researchers have revealed the biological mechanisms by which a family of proteins known as histone deacetylases (HDACs) activate immune system cells linked to inflammatory bowel disease (IBD) and other inflammatory diseases.
A white blood cell.
News

Promising Treatment Approach for Aggressive Leukemia Identified

Blocking oxygen-sensing enzymes in cancer cells can significantly halt acute myeloid leukemia in patient samples without affecting the production of normal blood cells.
Enhanced scanning electron microscopy (SEM) image of cancer malignant cells with high magnification of the cells surface
News

Cancer Cells’ Shapeshifting Ability Reveals New Drug Targets

Using a novel imaging technique to view cells in 3D, researchers have been able to identify two genes that control how melanoma skin cancer cells change shape – offering potential drug targets to prevent the cancer from spreading.
A lab worker pipetting media into a cell culture dish.
Industry Insight

Recreating Organ-Specific Tumor Environments In Vitro

At ELRIG’s Research & Innovation 2024 event, Technology Networks spoke to Dr. Véronique De Conto, project leader in in vitro pharmacology at HCS Pharma, to learn more about their powerful tools for in vitro metastasis propagation.
High magnification micrograph of microglia cells stained with Rio-Hortega's method (silver carbonate). This type is the ramified or resting microglia that appears in normal brain tissue.
News

Mobilizing Microglia in the Fight Against Alzheimer’s Disease

Recently approved Alzheimer's drugs work by tagging amyloid plaques for clearance by the brain's microglia. Washington University School of Medicine in St. Louis researchers are developing an alternative approach, using a homemade antibody to directly mobilize microglia.
A 3D model of a human brain.
News

A New Genetic Variant That Protects Against Alzheimer’s

Columbia researchers have discovered a genetic variant that reduces the odds of developing Alzheimer’s disease by up to 70% and may be protecting thousands of people in the United States from the disease.
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