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Drug Targets – News and Features

Double helix structure of DNA.
News

Genetic Variants in Two Genes Finds Six-Fold Impact on Obesity Risk

Cambridge researchers have identified genetic variants in two genes that have some of the largest impacts on obesity risk discovered to date.
A blue-green pill in the middle of white tablets.
News

Discovery May Reduce Dependence on Animals for Anti-Clotting Drug

Researchers have developed a process to bioengineer heparin, the world’s most widely used blood thinner, which is currently derived from pig intestines.
Pills spill form a prescription bottle.
News

Issue Hampering Pancreatic Cancer Drug Combination Identified

Researchers have identified two enzymes that work against the chemotherapy drug gemcitabine, preventing it from treating pancreatic cancer.
Cancer cells.
News

Targeting Cancer-Fueling Proteins Shows Potential for Treating Aggressive Leukaemia

Researchers have found a new way to potentially treat one of the most common forms of acute lymphoblastic leukaemia. The study was able to kill leukaemia cells in the lab and stop cancer cells from growing.
A bacteriophage.
News

First Look at Atom-Level Structure of Packaged Viral Genome

The first atom-level model of a DNA-packed viral capsid reveals genome structure and possible new drug targets, University of Illinois researchers report.
An anxious young woman with her head in her hands.
News

Genetic “Switch” Controlling Anxiety Discovered

A genetic "switch" has been identified that plays a role in controlling anxiety levels, which researchers hope could provide a new anxiety drug target.
A row of pipettes filled with red liquid
Article

High-Throughput Screening: Advances, Applications and Combined Approaches

In this article, we highlight various high-throughput screening strategies being used to interrogate large libraries of compounds and hear from researchers working to further streamline specific approaches to increase speed and improve quality and accuracy.
A strand of RNA.
News

Study Finds Why Some RNA Drugs Are More Effective Than Others

The field of RNA therapeutics is booming. But not all drugs are created equal. CSHL scientists Justin Kinney and Adrian Krainer recently teamed up to investigate why some RNA-splicing-based therapies work better than others.
White pills on a blue background.
News

Regenerative Hearing Drug Assessed in World-First Trial

UCL and UCLH researchers have successfully completed a world-first trial of a therapy designed to restore hearing loss.
A male patient with a doctor.
News

Understanding the Genetics of Male Breast Cancer

Male breast cancer represents less than 1 percent of all breast cancer cases each year. Unlike breast cancer in women, survival rates for men haven't significantly improved in the last 30 years, according to the National Cancer Institute.
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