Gene and Cell Therapy – News and Features

Research from Martin Luther University suggests the asthma drug theophylline helps reduce symptoms in ADCY5-related dyskinesia, a rare genetic movement disorder. Most patients reported fewer involuntary movements, improved walking and better sleep.

An international clinical trial led by WashU Medicine researchers shows an innovative CAR-T cell immunotherapy is promising against aggressive T cell cancers and has manageable side effects.

A dual-target CAR T-cell therapy approach shows promise for slowing tumor growth in a notoriously aggressive and fast-growing brain cancer. Tumors became smaller after the experimental CAR T-cell therapy in nearly two-thirds of patients.

Learn how CD34+ stem cells may help heart attack patients recover. A look at cutting-edge cell therapies and what's coming next in cardiac care.

University of Michigan researchers have identified herpes virus saimiri, which infects the T cells of squirrel monkeys, as a source of proteins that activate pathways in T cells that are needed to promote T cell survival.

Researchers at the University of Barcelona discovered the RTP801 protein's key involvement in Alzheimer’s cognitive decline, specifically within astrocytes. Silencing RTP801 in animal models improved brain network connectivity and GABA production.

Researchers at NIH developed a dual-graft surgical method that allows the placement of two tissue grafts in the retina, enhancing research into therapies for dry age-related macular degeneration (AMD).

Researchers have developed a platform that delivers genetic material into immune cells with high efficiency, offering a safer, faster and more scalable way to manufacture cell therapies for cancer, including hard-to-treat solid tumors.

Researchers have developed the first vascularized organoid model of pancreatic islet cells, which promises to improve diabetes research and cell-based therapies.

Discover the latest in cystic fibrosis treatment, from CFTR modulators to ENaC blockers and emerging inhalable gene therapies.