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Gene and Cell Therapy – News and Features

Microbes in the gut lining.
News

Changing the Gut Microbiome May Improve Outcomes for Some Kidney Cancer Patients

Modulating the gut microbiome during immunotherapy treatment could improve outcomes for advanced kidney cancer patients, a phase 1 trial indicates.
Cell therapy.
News

CAR T-Cell Production Pioneered Using “Ultra-Small” Bioreactor

This is the first demonstration of T-cell culture in a microfluidic chip the size of a pack of cards, allowing the miniaturisation of CAR T-cell production for cancer treatment.
An assortment of pills.
News

Common Blood Pressure Drug May Improve Chemotherapy Response to Leukemia

Researchers found that a targeted gene therapy may make acute myeloid leukemia (AML) more sensitive to chemotherapy, while also protecting the heart against toxicity often caused by cancer treatments.
Stem cells under a microscope.
News

Stem Cell Breakthrough Offers Hope for Rare Disease

A new study led by researchers at UCL and the University of Sheffield, has demonstrated the potential of stem cell therapy to treat those with Hirschsprung disease.
Yersinia enterocolitica.
News

A Cutting-Edge Approach to Bacterial DNA Manipulation

A team led by the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg has now introduced a novel approach that can make many more bacteria amenable to genetic engineering.
Noninvasive gene delivery to the brain with the new engineered vector (green) or a commonly-used gene therapy vector (red).
News

Potential Non-Invasive Gene Therapy Approach for Brain Disorders Developed

A new method offers hope for treating brain disorders through gene therapy. The innovative approach could transform treatments for inherited conditions and mental health issues by targeting specific regions of the brain with newfound precision.
A 3D model of a human heart.
News

Mitochondrial Transfer Revives Damaged Heart Muscle

Transferring mitochondria from a patient’s healthy skeletal muscle to damaged, ischemic heart tissue has been shown to restore heart muscle, increase energy production, and improve ventricular function.
Scientists in a lab looking at a laptop screen.
News

seekRNA Offers a Stand-Alone “Cut-and-Paste” Tool for Gene Editing

Patented method developed in the laboratory of Dr Sandro Ataide promises to accelerate the potential of genetic engineering already shown by CRISPR gene-editing technology.
Medical tubes attached to a persons hand.
News

Nanowire Approach Helps To Enhance T-Cell Therapy

Researchers have developed a solution to retain the naïve state of cells in adoptive T-cell therapy, allowing them to be even better disease fighters when they are infused back into a patient.

A thin electronic sensor on a gloved finger.
News

New “Smart Bandages” Have Potential to Revolutionize the Treatment of Chronic Wounds

"Smart bandages" that can automatically sense and respond to changes in a wound could revolutionize chronic wound treatment, including diabetic ulcers and surgical wounds.
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