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Gene and Cell Therapy – News and Features

A purple human brain.

Gene Delivery Vehicle Shows Promise for Human Gene Therapy

Scientists have engineered an adeno-associated virus (AAV) that efficiently crosses the blood-brain barrier in human cell models and delivers genes throughout the brain in humanized mice.
A scientist holding up a vial containing an image of a DNA double helix.

Top Trends Shaping Pharma in 2024: AI, Gene Editing, Biosimilars and Real-World Data

From AI's transformative role in drug discovery and CRISPR breakthroughs to the rise of biosimilars and real-world data. Learn how these innovations are reshaping pharma and driving progress in 2024.
A white mouse walking over test tubes.

Novel Gene Therapy Targets Disc-Related Back Pain

An estimated 40% of low-back pain cases are attributed to degeneration of the cushiony intervertebral discs that absorb shocks and provide flexibility to the spine.
Gloved hand using tweezers to remove a test tube from liquid nitrogen.

Overcoming Obstacles in Automating Cryogenic Storage

This article explores the challenges and strategies involved in transitioning to automated cryogenic storage systems. From assessing current infrastructure to gaining organizational buy-in and selecting appropriate containers, follow these steps to help ensure a successful transition to automated cryogenic storage.
A man in t-shirt and shorts runs along a path.

Experimental Drug Makes Exercise Easier for People With Common Heart Condition

An experimental drug can increase oxygen uptake in people with hypertrophic cardiomyopathy, making it easier for them to exercise and carry out day-to-day tasks.
A scanning electron microscope image of virion.

Gene Therapy Eliminates 90% of Herpes Infection in Mouse Models

Preclinical studies of a new gene therapy show it can eliminate 90% or more of herpes infection and suppress how much virus can be released by an individual.
A cancer cell is attacked by T cells.

CAR T-Cell Therapy Could Be Adapted for Solid Tumors, Study Finds

CAR T-cell therapy could be adapted to target solid tumors, potentially transforming cancer treatment.
Two researchers in a lab.

CRISPR Gene Editing Therapy Improved Vision in Trial for Inherited Blindness

Results from a clinical trial of CRISPR gene editing in 14 individuals with a form of inherited blindness show that the treatment is safe and led to measurable improvements in 11 of the participants treated.
The inside of a cell, featuring A4Cell's microchip.
Industry Insight

Monitor What’s Happening Inside Your Cells in Real Time

At ELRIG’s Research and Innovation 2024 event, Technology Networks spoke with A4Cell to learn about its SPAchip® technology, which consists of intracellular silicon microchips that monitor cellular pathways in real time.
A strand of DNA, with one section lit up.

Exploring the Microbiome Reveals Novel Treatments for Genetic Disorders

A new CRISPR-Cas9 molecule produced by a bacterium in the gut microbiome could have clinical potential to treat genetic diseases.