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Light Microscopy – Multimedia

Inhibition of The Auto-inflammation Suppressor Protein ISG15 Triggers Preeclampsia by Blocking Trophoblast Migration and Invasion content piece image
Poster

Inhibition of The Auto-inflammation Suppressor Protein ISG15 Triggers Preeclampsia by Blocking Trophoblast Migration and Invasion

In summary, ISG15 expression levels are crucial for trophoblast morphology and function (migration/invasion). By blocking trophoblast invasion, reduced ISG15 levels could contribute to impaired spiral artery transformation that reduces utero-placental blood flow in preeclampsia. Thus, agents inducing ISG15 expression are likely to be therapeutic in preeclampsia.
7 Stunning Cell Images from 2017  content piece image
Listicle

7 Stunning Cell Images from 2017

Advances in imaging techniques now enable us to see cells in exquisite detail. This has not only increased what researchers can learn about cells’ development and behaviour, but has also resulted in the production of some images beautiful in their own right.

Here we take a look at a few of our favourite cell images from the past year.
6 Ultra-Low Cost Diagnostics content piece image
Listicle

6 Ultra-Low Cost Diagnostics

In this list we look at 6 promising ultra-low cost diagnostic technologies, which could help take the tools to where they are most needed.
Cross-disciplinary Optimization of Nano-Drug Delivery to Ovarian Carcinoma and Glioma Cells content piece image
Poster

Cross-disciplinary Optimization of Nano-Drug Delivery to Ovarian Carcinoma and Glioma Cells

This study reports on the quantitative analysis of the diffusion and localization of a targeted drug delivery system (DDS) consisting of fluorescent labeled 0.01 µM paclitaxel-BODIPY 564/570 encapsulated in non-ionic surfactant vesicles embedded in a thermosensitive cross-linked chitosan hydrogel.
Imaging Gene Regulation in Living Cells at the Single Molecule Level content piece image
Video

Imaging Gene Regulation in Living Cells at the Single Molecule Level

In this talk, James Zhe Liu presents his teams latest efforts in harnessing a set of advanced super-resolution, single-molecule imaging approaches to study how enhancer-binding pluripotency factors (Sox2/Oct4) dynamically search for and assemble on their cognate sites in live embryonic stem (ES) cells.
Chemists Know - (Parody of "Let It Go" from Frozen) - University of California Irvine content piece image
Video

Chemists Know - Let It Go Parody

Chemists know, wouldn't YOU like to know?
App Note / Case Study

Monitoring Saccharomyces Cerevisiea Growth with Bright Field Microscopy in Real Time

Strains of the yeast Saccharomyces cerevisiea serve critical roles in the production of many different products including food staples, medicines, and biofuels. The ability to obtain the desired product reliably and repeatedly requires careful monitoring of not only the input materials, but the growth of the yeast strain during the process.
Super-resolution Single Molecule Localization Microscopy of the Exocytotic Machinery Underlying Insulin Secretion content piece image
Poster

Super-resolution Single Molecule Localization Microscopy of the Exocytotic Machinery Underlying Insulin Secretion

Single molecule imaging of the tSNARE proteins involved in insulin secretion.
Cell Culture and Cell Analysis using the Real Architecture for 3D Tissue (RAFT™) Culture System content piece image
Poster

Cell Culture and Cell Analysis using the Real Architecture for 3D Tissue (RAFT™) Culture System

This poster explains how standard analysis techniques, like fluorescence microscopy, can be applied easily to RAFT™ 3D Cell Cultures.
App Note / Case Study

Characterization of Protein Aggregates in Suspension and on a Filter Membrane by Morphologically-Directed Raman Spectroscopy

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