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Multiomics – News and Features

John Lesica, president, chromatography and mass spectrometry at Thermo Fisher Scientific.
Industry Insight

Optimizing Analytical Tools To Accelerate Translational Research

John Lesica, president of chromatography and mass spectrometry at Thermo Fisher Scientific, joined Technology Networks for an interview at this year's American Society for Mass Spectrometry event.
A green field.
Article

CRISPR-Cas9 Editing in Plants: What's the Latest Research?

In this article, we take a look at the latest advancements in research applying multiplex CRISPR-Cas9 genome editing to plants.
A mother and her baby.
News

Digital Babies Created To Simulate the First 180 Days of Life

Whole-body models (WBMs) are computational models that integrate different types of multiomics data such as genomic, metabolic and proteomic insights, and have been created to simulate and study adult physiology and disease. WBMs for newborns, however, are currently lacking – until now.
A scientist places a sample under a microscope
News

Machine Learning Reveals Key Differences in Inner Workings of Immune Cells

Thanks to a particular cellular architecture, more than half of all killer T cells are able to mount a faster and stronger response to pathogens.
Stem cells.
News

Gut Stem Cell Research Reveals Mistaken Cellular Identity

Two independent studies by Columbia scientists suggest that research into the gut’s stem cells over the past 15 years has been marred by a case of mistaken identity: Scientists have been studying the wrong cell.
DNA double helix with 5mC and 5hmC methylation modifications indicated.
Industry Insight

Picking Apart the Epigenome To Advance Cancer Research

Both genetic and epigenetic sample information is required to get the full picture. Six-base genome sequencing enables this without need of multiple techniques, laborious downstream data processing or data loss, and cancer research is benefiting.
A thin slice of part of a Sorghum bicolor shoot apex.
News

The Potential of Bioenergy Sorghum for Sustainable Biofuels

Bioenergy sorghum is an important resource for the production of biofuels and bioproducts. Researchers have been working hard to make this tall, drought-tolerant plant even more productive and resilient to harsh environmental conditions.
A child looking through a toy.
News

Genetic Risk Factors for Autism Linked to Distinct Cellular Changes

A new single-cell study from the PsychENCODE initiative links genetic risk factors to cellular changes in ASD brains. The research, published in Science, provides insight on the potential causal mechanisms behind ASD.
A girl sitting on a chair looking out a window.
News

PTSD and Depression Have Shared and Distinct Brain Molecular Dysregulations

McLean Hospital researchers uncovered both shared and distinct molecular changes across brain regions, genomic layers, cell types and blood in individuals with posttraumatic stress disorder (PTSD) and major depressive disorder (MDD).
Two doctors stitching a patient after surgery
News

How Cells React to Pig Heart and Kidney Transplants in Humans

Two new studies reveal changes at the single-cell level in the organs and recipients’ bodies before, during and after transplantation with genetically modified pig organs in decedents.
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