PCR – News and Features

By improving sensitivity and boosting signal amplification, nanomaterials are heralding a new era for biomarker detection.

This article explores the latest advancements in food testing and highlights how they are enabling faster, more reliable testing to ensure the safety of the global food supply chain.

Having more copies of the AMY1 gene – which normally controls the production of a saliva enzyme – may be protective against Type 2 diabetes, a new study suggests.

Scientists have developed a new paper-based device that can improve the diagnosis of malaria in asymptomatic people. In field tests in Ghana, the device outperformed the current gold standard methods being used in the country's hospitals.

A new portable device developed by Rutgers University researchers can detect genetic mutations linked to hereditary transthyretin amyloidosis in just 10 minutes. The device provides a rapid and accessible diagnostic tool for genetic diseases.

A study introduces a CRISPR model that predicts gRNA activity more accurately using chemically synthesized gRNAs. The model also improves homology-directed repair (HDR) efficiency, offering insights into CRISPR editing precision and safety.

The study explored the use of metagenomic next-generation sequencing (mNGS) for identifying pathogens in pulmonary infections.

A large 4-year randomized trial found that daily vitamin D3 supplements help slow the shortening of telomeres in healthy older adults. Participants taking 2,000 IU of vitamin D3 lost around 140 fewer base pairs than those on placebo.

A Japanese research team profiled genome-wide DNA methylation in the dorsal raphe nucleus of autism and control brains. They discovered abnormal methylation in genes related to sensory processing and serotonin signaling.

Liquid biopsies offer a less invasive, yet highly informative, alternative to traditional diagnostic methods. This article examines how liquid biopsies are aiding cancer drug development and guiding treatment strategies.