Pharmacovigilance – Multimedia

Did you know that the adverse effect of drugs on cardiac tissue – known as cardiotoxicity – is one of the principal reasons that therapeutics are withdrawn from the market?

Immunotherapy aims to leverage the power of the immune system in the fight against cancer. It offers a more effective and less destructive approach than many traditional treatments.

Protein-targeting chimeras (PROTACs) have gained significant attention recently due to their high potency in nanomolar drug concentrations and target selectivity. However, low test concentrations in complex matrices present analytical challenges.

Speaking at The Landscape of Cancer Research 2022 online symposium, James Moon from the University of Michigan delivered his talk on next-generation STING agonists for immunotherapy against advanced cancer.

In this video, Jonathan from the Institute of Human Anatomy discusses how Viagra works to assist with erectile dysfunction.

Sugar free gummies are delicious, low on calories, and… technically laxatives? Reactions producer Andrew dives into the science to figure out how he can make delicious sugar free gummies without the uncomfortable side effects.

The hypothalamic-pituitary-thyroid axis (HPT axis) is conserved across vertebrate evolution. Perturbation of thyroid hormone homeostasis (THH) can lead to adverse effects in thyroid function affecting growth, metabolism and cognitive function.

Glycosylation is a common post-translational modification (PTM) that plays a critical role in antibody effector functions. Comprehensive characterization of N- and O-linked glycosylation in protein therapeutics is essential for ensuring drug safety and efficacy.

Speaking at Drug Discovery & Development online symposium 2021, Pei Liu from GenScript, presented her talk on monoclonal antibodies.

This listicle highlights five commonly used cell viability assays and their benefits and limitations in immunotherapy potency testing.