Pharmacovigilance – News and Features

News
Most Effective Treatments for Chronic Hives Identified
A new international study led by researchers at McMaster University has identified the most effective and safest treatments for people suffering from chronic urticaria, more commonly known as chronic hives.

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Patients With Drug-Resistant TB Benefit From Personalized Treatment Regimens
Some patients with highly drug-resistant tuberculosis could benefit from a shorter treatment with fewer drugs while others may warrant more aggressive therapy, according to the findings of a new study.

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Amino Acids Regulate How Cells Respond to Drugs
Amino acids work together to regulate the cellular response to certain drugs, which could help develop more effective and safer treatments, according to an international study.

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Targeted Radiotherapy Shown To Match Whole-Breast Treatment for Low-Risk Cancer
A long-term clinical trial has shown that targeted radiotherapy is just as effective as whole-breast treatment for controlling low-risk breast cancer, while reducing the likelihood of side effects.

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Penicillin Allergy Testing Could Be Key to Combating Antibiotic Resistance
Removing incorrect penicillin allergy labels on GP records could combat antibiotic resistance and save lives, an NIHR-funded clinical trial led by the University of Leeds has found.

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Previously Unknown Gateway Into Cells Could Make Gene Therapies Safer
Scientists identified a previously unknown gateway into human cells, a receptor called AAVR2, that gene therapy viruses use to deliver therapeutic genes. This newly uncovered pathway could allow lower doses of virus to be used in treatment.

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Lessons on Long COVID From Feline Coronavirus
Scientists have found that mesenchymal stromal cells, or MSC therapy, in combination with antiviral drugs, helped cats’ immune systems recover and reduced systemic inflammation.

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Scalp Cooling Helps Reduce Chemotherapy-Related Hair Loss
Researchers have found that combining scalp cooling treatment with antioxidants can significantly reduce or even prevent the damage to hair follicles caused by chemotherapy drugs.

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Long-Term Survival Rates Favorable for Prostate Cancer Patients
A new population-level study from Uppsala University has found that most men treated for non-metastatic prostate cancer according to current clinical guidelines have a favorable long-term prognosis.

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Disrupting the Cell Feedback Loop Fueling Leukemia
Researchers have identified a signaling loop involved in the growth and persistence of leukemia cells, and developed a novel immunotherapy that can disrupt that loop to boost immune function and improve survival.
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