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Pharmacovigilance – News and Features

Illustration of the concept of weight loss using drugs.
Article

Balancing Weight Loss and Muscle Health in the Age of Incretin-Mimetic Drugs

Incretin-mimetic drugs contribute to dramatic weight loss, but this does not solely mean fat loss. In this article, we explore the impact of incretin-mimetic drugs on muscle health and what can be done to limit these severe side effects.
A girl doing sit ups on a yoga mat.
News

Strength and Fitness Linked to Lower Risk of Death for People With Cancer

A study finds that muscular strength and cardiorespiratory fitness significantly reduce mortality risk in cancer patients. Those with higher fitness levels had up to 46% lower risk of death from any cause.
Vibrant blue microscopic image of cells
News

Single Dose of Drug Candidate Eliminates Breast Cancer Tumors in Mice

Researchers have created a novel treatment that eliminated small breast tumors and significantly shrank large tumors in mice in a single dose, without problematic side effects.
Pregnant woman
News

Fewer Than 1% of US Clinical Drug Trials Enroll Pregnant Participants

An analysis by researchers at the Brown University School of Public Health found that most studies exclude participants who are pregnant, potentially leaving critical safety and efficacy questions unanswered.
Illustration of brain from digital networks to visualise artificial intelligence.
News

Streamlined Protein Redesign To Enhance Ligand Binding

The ability to alter protein binding can create tailored therapeutics with reduced side effects, sensitive diagnostic tools, targeted drug delivery and sustainable bioremediation.
A blue and pink pill on a blue background.
News

Potential Pancreatic Cancer Treatment Shows Promise

An antibody–drug conjugate could offer hope for pancreatic cancer treatment.
A person holding mushrooms.
News

Psychedelic Therapy May Help Improve Cancer Patients’ Mental Health

The “magic mushroom” psychedelic compound – psilocybin – may help to improve mental health symptoms faced by cancer patients when used alongside psychotherapy.
Cancer cells.
News

Bacteria Developed To Deliver Cancer-Fighting Drugs Directly to Tumors

Scientists at UMass Amherst and Ernest Pharmaceuticals developed BacID, a bacterial cancer therapy activated by aspirin. This targeted approach delivers drugs directly into tumors, sparing healthy tissue and improving safety.
The bone marrow of a mouse with a myeloproliferative neoplasm (left) shows fibrosis, or scar tissue (horizontal lines). A mouse with the same disease treated with an RSK1 inhibitor shows bone marrow resembling normal tissue (right).
News

Breast Cancer Trial Drug May Also Treat Blood Cancers

Two new studies led by researchers at Washington University School of Medicine in St. Louis have identified a possible way to block the progression of several forms of blood cancer using a drug already in clinical trials against breast cancer.
White immune cells attack a yellow cancer cell, symbolizing immunotherapy.
News

Off-the-Shelf Immunotherapy Approach Shows Promise for B-Cell Lymphoma

A new type of off-the-shelf cell-based immunotherapy shows promise for B-cell lymphomas, and could make make future cellular immunotherapies less expensive and more accessible.
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