Pharmacovigilance – News and Features

Article
Balancing Weight Loss and Muscle Health in the Age of Incretin-Mimetic Drugs
Incretin-mimetic drugs contribute to dramatic weight loss, but this does not solely mean fat loss. In this article, we explore the impact of incretin-mimetic drugs on muscle health and what can be done to limit these severe side effects.

News
Strength and Fitness Linked to Lower Risk of Death for People With Cancer
A study finds that muscular strength and cardiorespiratory fitness significantly reduce mortality risk in cancer patients. Those with higher fitness levels had up to 46% lower risk of death from any cause.

News
Single Dose of Drug Candidate Eliminates Breast Cancer Tumors in Mice
Researchers have created a novel treatment that eliminated small breast tumors and significantly shrank large tumors in mice in a single dose, without problematic side effects.

News
Fewer Than 1% of US Clinical Drug Trials Enroll Pregnant Participants
An analysis by researchers at the Brown University School of Public Health found that most studies exclude participants who are pregnant, potentially leaving critical safety and efficacy questions unanswered.

News
Streamlined Protein Redesign To Enhance Ligand Binding
The ability to alter protein binding can create tailored therapeutics with reduced side effects, sensitive diagnostic tools, targeted drug delivery and sustainable bioremediation.

News
Potential Pancreatic Cancer Treatment Shows Promise
An antibody–drug conjugate could offer hope for pancreatic cancer treatment.

News
Psychedelic Therapy May Help Improve Cancer Patients’ Mental Health
The “magic mushroom” psychedelic compound – psilocybin – may help to improve mental health symptoms faced by cancer patients when used alongside psychotherapy.

News
Bacteria Developed To Deliver Cancer-Fighting Drugs Directly to Tumors
Scientists at UMass Amherst and Ernest Pharmaceuticals developed BacID, a bacterial cancer therapy activated by aspirin. This targeted approach delivers drugs directly into tumors, sparing healthy tissue and improving safety.

News
Breast Cancer Trial Drug May Also Treat Blood Cancers
Two new studies led by researchers at Washington University School of Medicine in St. Louis have identified a possible way to block the progression of several forms of blood cancer using a drug already in clinical trials against breast cancer.

News
Off-the-Shelf Immunotherapy Approach Shows Promise for B-Cell Lymphoma
A new type of off-the-shelf cell-based immunotherapy shows promise for B-cell lymphomas, and could make make future cellular immunotherapies less expensive and more accessible.
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